Wednesday, November 13, 2019


10:00 Welcome

Global Perspectives in Healthcare

Chair Cassandra Melvin
10:05 Global Health Care Challenges and Trends
  Benjamin Wiegand, Global Head World Without Disease Accelerator, Janssen Pharmaceutical Companies of Johnson & Johnson
Perspectives on Healthcare, the Medtech Industry, and Digital
  Michael Strübin, Director Digital Health, MedTech Europe
Perspectives on Healthcare, the Medtech Industry, and Digital
Michael Strübin

Michael Strübin
Director Digital Health
MedTech Europe

Michael Strübin

Healthcare represents one of the biggest sectors in advanced industrialised countries (the OECD average in 2017 was 8.8 percent of GDP), yet as a market it may be one of the most complicated to access: fragmentation, the strong role of the public sector, the high level of regulation, the often competing interests of powerful stakeholders, and other factors make life difficult for industry. New regulations for medical devices and in vitro diagnostic devices, enacted in 2016, will come into force in the coming years. And advances in technologies, especially in digital, have the potential to change and upend the doctor-patient relationship. These and more developments will be covered in this keynote from MedTech Europe, the largest trade association for the medtech industries in Europe.

Michael Strübin joined MedTech Europe as Digital Health Director in 2018 to help develop the industry’s voice in the digital health field and to represent MedTech Europe’s members vis-à-vis digital health policymakers and stakeholders.Prior to MedTech Europe, Michael ran the European operations of the Continua Health Alliance (renamed Personal Connected Health Alliance in 2014), an international association of health and technology companies, governments and research organisations to advance personal connected health. Between 2006 to 2008, Michael was the first European Director of the Health Information and Management Systems Society (HIMSS). Michael studied political science and humanities in Germany and the United States, and worked in international development and philanthropy. Since 2003 he has been based in Brussels.

10:55 TBD
11:20 Bringing the Power of Chip Technology to Healthcare
  Herlien Declerk, Business Development Manager, Life Sciences, imec
11:45 Bridging the Gap from Semiconductors to Medical Technologies

The Digitization of Preventive Healthcare

Chair Herlien Declerk
12:10 Opening
Digital Health: Tracking Mental Stress and Mood Using Wearable Data and Machine Learning
  Emmanuel Rios Velazquez, OnePlanet | Connected Health Solutions
Digital Health: Tracking Mental Stress and Mood Using Wearable Data and Machine Learning
Emmanuel Rios Velazquez

Emmanuel Rios Velazquez

OnePlanet | Connected Health Solutions

Emmanuel Rios Velazquez

Through wearable technology and digital footprints on our mobile phones, social media, etc., we can extract valuable insights on our lifestyle and well-being. imec is developing new tools to encourage behavior change towards a healthier lifestyle, that may lead to new therapeutic tools for patients with mental health problems such as depression or eating disorders.Through habit monitoring, physiological monitoring, and personalized, intelligent algorithms we aim to identify triggers of unhealthy behavior, increase awareness and contribute to preventive health.This talk will touch on data-driven machine-learning enabled applications linking wearable data and mental health.

Emmanuel is a data scientist engaged on the identification of relevant patterns of physiology and brain activity to assess cognition, mood and behavior through wearable technology, at imec's Connected Health Solutions team.Emmanuel received a PhD from the Maastricht University, on the use of heterogeneous patient data and computational imaging (radiomics) for decision-support systems in radiation oncology.This pioneering work led to diverse multi-centric, international scientific collaborations. This was followed by a post-doctoral degree at the Computational Imaging and Bioinformatics lab at the Dana-Farber Cancer Institute-Harvard Medical School, investigating the link between cancer imaging phenotypes and tumor biology for precision medicine.Besides crunching data, he likes reading (contemporary novels), playing drums and whenever possible going to the sea.

12:40 Can Wearables Help Prevent the Silent Killer, Blood Pressure?
  Sudhir Mulpuru, Director of Product Management Industrial and Healthcare Business Unit, Maxim Integrated
Sensors to Enable Consumer Health Applications
  Filip Frederix, Senior Marketing Manager Smart Medical Devices, ams
Sensors to Enable Consumer Health Applications
Filip Frederix

Filip Frederix
Senior Marketing Manager Smart Medical Devices

Filip Frederix

Healthcare costs are rising due to an aging population and with decreasing funds from governments and insurance companies, our society needs to implement efficient healthcare solutions and more critically, pay more attention to prevention, early diagnosis and remote monitoring. This explains the recent rise of consumer health solutions. In this abstract, we will discuss the requirements related to the sensor technologies in medical-grade devices. We will demonstrate various technology approach options in the field of point-of-care (POC) diagnostics and portable consumer health devices. To take full advantage of preventative care, it is important that people are able to frequently monitor their health status. Research shows that monitoring tools must be easy to use, non-evasive and connected, with the ultimate goal is for these tools to be used at home or at the GP´s office. POC testing or rapid tests have the potential to solve these challenges. A relevant example is the commonly used home pregnancy tests, which are based on the lateral flow testing principle. At ams, we developed an electronic/optical readout for these tests to boost the sensitivity and enable multiplex capabilities. We will highlight a first prototype of this technology and its performance. We will also present the VivaVita, which is a result of a corporation between Joysys and ams. We will explain the working principle, the specifications and the applications. The VivaVita device allows generating medical quality data at a consumer level or outside a hospital setting. The VivaVita measures heart rate variability, ECG and blood pressure with a small, portable and fully integrated device. It is operated in a consumer friendly way, it is cost-effective and enables wireless data transfer and wireless charging. The core of the device is the AS7026 module, which is a low power, fully integrated optical module that allows for photo plethysmography (PPG) measurements in a reliable way.

Filip Frederix has worked for more than 20 years in the field of nanotechnology for healthcare products and is author of several publications and patents. Filip joined ams in October 2017 to spearhead the ams marketing efforts for Smart Medical Devices within the Imagine New Sensor Division. With a proven track-record in starting new business opportunities, Filip´s background includes working as an independent consultant supporting life sciences startups with capital raising and their business strategy. The largest part of his career was spent at NXP as a program director and new business development manager for healthcare products. In 2004 Filip won the prestigious DSM award, where he continued to work on emerging business projects at DSM in the Netherlands. While working as a post-doctoral researcher at IMEC, he earned his PhD degree in Chemistry from the University of Leuven in 2004. He serves as part-time professor at the University of Hasselt (since 2013).

13:30 Monitoring Sleep to Prevent Health Issues and Costs
  Tapan Shah, Principal Member of Technical Staff Industrial and Healthcare Business Unit, Maxim Integrated



Revolutionizing Healthcare with Personalized Medicine

Chair Henry Leistner, Team Leader | Micro Dosing Systems, Fraunhofer EMFT
Henry Leistner

Henry Leistner
Team Leader | Micro Dosing Systems
Fraunhofer EMFT

Henry Leistner

Henry Leistner is holding a Master's degree in Semiconductor Physics and in Industrial Engineering. His previous research activities focused on yield enhancement methods at X-FAB Silicon Foundries. Further he investigated improvement strategies in customer supply allocation with machine learning at Infineon Technologies. Since 2018, he has been leading a team of the Micro Dosing Systems department of Fraunhofer EMFT, covering a broad range from applications, feasibility studies and consulting activities in medical technology (e.g. artificial pancreas, insulin patch pumps) to consumer electronics (e.g. environmental sensors in smartphones). Additionally, he is pursuing a PhD in Electrical Engineering at Technical University of Munich.

14:15 Precision Medicine: Toward Innovative Solutions to Meet Healthcare Challenges
  Jerome Mouly, Senior Analyst & Business Developer, Yole
14:40 Companion Diagnostics
15:05 Innovative Diagnostics
15:30 Precise Drug Delivery for Personalized Healthcare
  Dr. Martin Richter, Head of Department Micromechanics, Actuators and Fluidics, Fraunhofer EMFT
15:55 Enabling Personalized Medicine with MEMS Manufacturing
  Stefan Ernst, Manager Business & Strategy MEMS, X-FAB

Technology Demo Zone & Networking

  Participating companies: MedTech Europe, Yole, imec, Fraunhofer, Sensome, ChronoLife, Onera Health, PKvitality, IC’Alps


Thursday, November 14, 2019

The Digital Patient: The Future of Artificial Organs & Human Avatars

Chair Patrick Boisseau, Director EU R&I Partnerships Policies, MedTech Europe
Patrick Boisseau

Patrick Boisseau
Director EU R&I Partnerships Policies
MedTech Europe

Patrick Boisseau

Patrick Boisseau is the Director, EU Research & Innovation Partnership Policies at MedTech Europe, the EU association of medtech and in vitro diagnostics industries, based in Brussels (Belgium). He is a core member of the Inter Association Task Force setting up the future Public Private Partnership on Health Innovation under Horizon Europe.Until recently Patrick was VP Europe at CEATech Healthcare Institute, based in Grenoble (France). He managed a significant number of EU collaborative projects, research infrastructures, coordination actions and networks of excellence for the past 20 years. His scientific and technical expertise focuses on innovative medical technologies.

10:00 Day Two Opening
  Patrick Boisseau, Director EU Research & Innovation Partnerships Policies, MedTech Europe
10:05 Human Avatars, the Next Paradigm in Healthcare
  Adrian Ionescu, Professor at EPFL Lausanne
10:30 Organ-on-Chip
10:55 The Digital Patient: Will We One Day Have our Own Health Avatars?
  Philips Ger Janssen, Department Head Multiphysics & Optics and Program Manager Patient Digital Twin, Philips
11:20 The Future of Personalized Treatment
  Dr. Franz Laermer, Project Director, Robert Bosch GmbH
11:45 The Clinician’s Point of View
  Prof. Anthony Mathur, Director of Interventional Cardiology, Bart's Heart Centre


12:40 Panel discussion

Key Drivers Transforming Healthcare: AI, Big Data and Cyber Security

Moderation Georg Heidenreich, Siemens Healthcare GmbH

Georg Heidenreich

Siemens Healthcare GmbH


Pioneering Research in Medical Technologies

Chair Anne Van den Bosch
13:25 CMOS Compatible SiN Technology Platform for Life Science Applications
  Andim Stassen, Process Integration Engineer, Life Science Process Integration Group, PhD candidate in Physics, KU Leuven
Microfluidic, CMOS Microelectrode Array-based Organ-on-chip System: a Platform for Personalized Medicine
  Thomas Pauwelyn, Postdoctoral Researcher, imec
Microfluidic, CMOS Microelectrode Array-based Organ-on-chip System: a Platform for Personalized Medicine
Thomas Pauwelyn

Thomas Pauwelyn
Postdoctoral Researcher

Thomas Pauwelyn

Healthcare has traditionally focused on one-size fits-all medication to treat populations instead of tailoring treatments to individual patients. Recent advances in stem cell technology, allow researchers to create models of diseases or individual patients for personalized medicine. Although organ-on-chip devices expose these models to a more physiological cellular environment, these devices face significant challenges including assay throughput, signal quality, and scalability of production.To address these challenges, imec developed a 16k CMOS-based microelectrode array with 16 independent, microfluidic chambers. This platform offers both scalability in fabrication and assay throughput. Further micropatterning of the surface allows for a structured growth that better resembles a specific organ. By combining these devices with patient-specific cell models, these platform shows great potential for cardiac, neuronal, and oncological applications in the field of personalized medicine.

Dr Thomas Pauwelyn has studied at KU Leuven, Belgium, since 2008. He earned his BSc in Bioscience Engineering specializing in Catalytic Technologies in 2011 and a Master’s in Nanoscience and Nanotechnology with the Bioscience Engineering option in 2013. He then received an IWT fellowship to do a PhD at KU Leuven and imec’s Life Science Technologies group, which finished in 2018.Thomas is currently working as a post-doctoral researcher with an Innovation Mandate grant from VLAIO, investigating strategies to valorize the results from his research. Thomas’s research focuses on developing novel organ-on-chip systems for predictive toxicology and drug development. He is also investigating how organ-on-chip devices may help stratify patients and help enable personalized medicine.


MedTech Startup Challenge

Chair Michael Kaiser
14:05 Smart Investments in Health
  Tom Vanhoutte, Partner, imec.xpand
14:20 TBD
  Franz Bozsak, CEO, Sensome
14:35 TBD
14:50 TBD
  Soukaina Adnane, Co-Founder & CCO, Onera Health
15:05 TBD
  Jean-Luc Triouleyre, CEO, IC’Alps
15:20 TBD
  Laurent Vanderbrouck, CEO, ChronoLife
15:35 TBD
  Luc Pierart, CEO and Founder, PKvitality
15:50 Closing by Session Chair
  Michael Kaiser, Managing Director, Smart Systems Hub GmbH